idiopathic retinal vasculitis, aneurysm, neuroretinitis: a significant increase in visual acuity after treatment with one session of panretinal photocoagulation, retinopexy and three consecutive intravitreal bevacizumab (avastin) injection

purpose: to report an idiopathic retinal vasculitis, aneurysm, neuroretinitis (irvan) case treated with one session of panretinal photocoagulation (prp) and intravitreal bevacizumab (avastin) case report: a 13-year-old boy was diagnosed as an irvan syndrome. systemic examination, fundus angiography, brain mri were performed to evaluate the patient. treatment with one session of prp, retinopexy and 3 consecutive monthly intravitreal injection of 1.25 mg bevacizumab was performed. after the second bevacizumab injection, complete regression of neovascularizations and improvement of visual acuity (va) to 3/10 for right eye and 6/10 for left eye was noted. by the other 2 additional monthly intravitreal injection of bevacizumab, va improved to 6/10 and 8/10 for right and left eye. the aneurysms became smaller. after 6 months of his treatment, his va was remained stable. conclusion: we reported a successful treatment effect of bevacizumab as an adjunctive therapy in combination with prp and retinopexy, for stage 3 irvan. bevacizumab seems to have promising effects in the treatment of irvan.   iranian journal of ophthalmology 201224(2):65-71 © 2012 by the iranian society of ophthalmology